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Year : 2017  |  Volume : 5  |  Issue : 3  |  Page : 271-274

Bronchiectasis and focal segmental glomerulosclerosis in rheumatoid arthritis

Department of Pulmonary Medicine, R. G. Kar Medical College, Kolkata, West Bengal, India

Correspondence Address:
Saurav Kar
8, Ganguly Bagan Lane, P.O. Mahesh, Hooghly, Serampore - 712 202, West Bengal
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1658-631X.213303

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A 28-year-old male patient who was a nonsmoker presented with bilateral symmetrical polyarthritis and polyarthralgia, suggestive of rheumatoid arthritis (RA), along with shortness of breath, fever and cough, suggestive of chronic renal failure and nephrotic range proteinuria. The chest radiograph was suggestive of panacinar emphysematous changes with bilateral central bronchiectasis. The patient reported that two of his brothers had died in their third decade because of renal failure. Renal biopsy showed focal and segmental glomerulosclerosis (FSGS). FSGS with panacinar emphysema and bronchiectasis is a rare entity in RA patients, and considering the possibilities of a familial pattern of FSGS, transient receptor potential cation channel 6 channelopathy was the most valid diagnosis.

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