Saudi Journal of Medicine and Medical Sciences

: 2015  |  Volume : 3  |  Issue : 1  |  Page : 1-

Nigella Sativa

Abdulaziz A Al-Quorain 
 Department of Medicine, College of Medicine, University of Dammam, Dammam, Saudi Arabia

Correspondence Address:
Abdulaziz A Al-Quorain
P.O. Box 40001, Al-Khobar 31952
Saudi Arabia

How to cite this article:
Al-Quorain AA. Nigella Sativa.Saudi J Med Med Sci 2015;3:1-1

How to cite this URL:
Al-Quorain AA. Nigella Sativa. Saudi J Med Med Sci [serial online] 2015 [cited 2023 Jan 30 ];3:1-1
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Full Text

Nigella sativa is a plant, common in South and Southwest Asia, Southern Europe, North Africa, Middle East and Saudi Arabia. [1] N. sativa is regarded as an important medicine for a variety of diseases. [2] Chemically, the black seed oil include various conjugated linoleic acids, namely thymoquinone, dithymoquinone, melantin, nigilline, tannin and others. [3]

The therapeutic activity of N. sativa is originated in the presence of thymoquinone. In large doses, nigilline is paralytic and melantin is toxic, requiring moderate use in spices and in folk medicine. [4] Various studies have shown that N. sativa has a wide spectrum of medicinal properties. A large number of experimental studies have been conducted on N. sativa seed all over the world. These studies proved that it can be used as antihypertensive, [5] antidiabetic, [6] antimicrobial, [7],[8] anti-inflammatory, analgesic, [9] gastroprotective, antioxidant and other activities. [10]

Aqueous suspension of the black seed has been used for these studies. Most of these, particularly on the gastroprotective qualities of the seed were well-designed and reproducible. Investigators "have ruled-out any bias or errors in the results." [11]

In view of the wide spectrum of conditions that N. sativa has been proved to be effective, drug companies are expected to have interest in this seed. Multi-center trials could be sponsored by these companies to further study the potential of this seed. One would expect this folk medicine to evolve one day into a global remedy, especially for various chronic diseases.

In this issue of our Journal, Dr. Abdulla Bamosa reviews the black seed; its pharmacological properties, activities and its uses in the management of type II diabetes mellitus.


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