Saudi Journal of Medicine and Medical Sciences

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 9  |  Issue : 3  |  Page : 235--240

Clinical profile and outcome of group B streptococcal colonization in mothers and neonates in Ras Al Khaimah, United Arab Emirates: A prospective observational study


Shatha Taher Salman AlZuheiri1, Rajani Dube2, Godfred Menezes3, Samar Qasem1 
1 Department of Obstetrics and Gynecology, Abdulla Bin Omran Hospital for Obstetrics and Gynecology, Ras Al-Khaimah, UAE
2 Department of Obstetrics and Gynecology, RAK Medical and Health Sciences University, Ras Al-Khaimah, UAE
3 Department of Microbiology, RAK Medical and Health Sciences University, Ras Al-Khaimah, UAE

Correspondence Address:
Rajani Dube
RAK Medical and Health Science University, PO Box 11172, Ras Al-Khaimah
UAE

Background: Maternal Group B Streptococcus (GBS)/Streptococcus agalactiae colonization rates vary worldwide; however, no such recent data are available from the United Arab Emirates (UAE). Objective: The objective of this study was to determine the prevalence of GBS colonization among pregnant women attending an antenatal clinic of a hospital in Ras Al Khaimah, UAE, along with the antibiotic sensitivity pattern, the clinical profile and pregnancy (maternal and fetal) outcome. Methods: This prospective observational study routinely offered rectovaginal swab for GBS to all women attending the antenatal clinic at 35–37 weeks of pregnancy between January and December 2019. MASTASTREP kit and Vitek-2 identification system was used for culture and identification. Women with positive cultures were followed up for any maternal and neonatal complications and the use of intrapartum antibiotic prophylaxis (IAP). Results: A total of 2295 women were included, of which 158 (6.9%) had positive cultures for GBS colonization. The carriage rate was higher in women without any risk factors for early-onset GBS disease (EOGBS) (P < 0.01). The GBS isolates were about 97% susceptible to linezolid and vancomycin, 90% to benzyl penicillin and 95% to ampicillin. Resistance to trimethoprim/sulfamethoxazole, clindamycin, erythromycin, and levofloxacin were about 77%, 57%, 57%, and 10%, respectively. Urinary tract infection in GBS colonized women were more common in those aged ≤30 years (P = 0.009). Fetal outcome was favorable in women receiving IAP for GBS colonization. No neonate had culture proven EOGBS. Conclusion: The prevalence of GBS colonization in pregnant women as well as the overall maternal and neonatal complications is low in Ras Al Khaimah, UAE. IAP is effective in preventing early-onset sepsis in newborn, and thus should be initiated in those with GBS colonization. The cultured GBS showed sensitivity to most antibiotics.


How to cite this article:
AlZuheiri ST, Dube R, Menezes G, Qasem S. Clinical profile and outcome of group B streptococcal colonization in mothers and neonates in Ras Al Khaimah, United Arab Emirates: A prospective observational study.Saudi J Med Med Sci 2021;9:235-240


How to cite this URL:
AlZuheiri ST, Dube R, Menezes G, Qasem S. Clinical profile and outcome of group B streptococcal colonization in mothers and neonates in Ras Al Khaimah, United Arab Emirates: A prospective observational study. Saudi J Med Med Sci [serial online] 2021 [cited 2021 Dec 7 ];9:235-240
Available from: https://www.sjmms.net/article.asp?issn=1658-631X;year=2021;volume=9;issue=3;spage=235;epage=240;aulast=AlZuheiri;type=0