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Figure 5: PI3/AKT-mediated Nrf2 signaling enhanced by RGN. (a) pAKT and pPI3K proteins after carrying out western blot analysis. (b) The pAKT, Nrf2, HO-1, and cleaved caspase3 were traced by western blotting. Data was represented as the mean ± SD of values (n = 3), and P < 0.05 represents key differences compared to DON alone. On the other hand, #P < 0.05 and RGN compared with the DON treatment groups

Figure 5: PI3/AKT-mediated Nrf2 signaling enhanced by RGN. (a) pAKT and pPI3K proteins after carrying out western blot analysis. (b) The pAKT, Nrf2, HO-1, and cleaved caspase3 were traced by western blotting. Data was represented as the mean ± SD of values (<i>n</i> = 3), and<i> P </i> < 0.05 represents key differences compared to DON alone. On the other hand, #<i>P</i> < 0.05 and RGN compared with the DON treatment groups